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Topiramate

Topiramate

Where is Topiramate used?

Topiramate is used to prevent and control seizures or epilepsy. This may also be used you prevent migraine headaches and lessen how often you get them. This is in the class of medications known as sulfamate-substituted monosaccharide anticonvulsants drugs. Topiramate acts on certain receptors, channels, chemicals, and enzymes in your brain to help prevent migraine headaches and control seizures. This is an FDA-approved medicine that is supplied as an extended-release capsule for oral use.

How does Topiramate work?

Topiramate works in different ways to prevent fits by calming the electrical nerve activity in the brain.

  • It affects the activity of two neurotransmitters in the brain. The drug enhances the action of GABA which is a neurotransmitter that acts as a natural nerve-calming agent. Topiramate also lessens the action of glutamate which is a neurotransmitter that normally has a nerve exciting effect.
  • This medicine also prevents sodium from entering the nerve cell. It is when they begin to fire rapid and repetitive electrical signals. This prevents the electrical signal from building up and passing on.

How is Topiramate taken?

  • Topiramate is usually taken twice a day or as directed by your doctor.
  • Each dose may be taken with or without food.
  • Take this medication by mouth with a full glass of water.
  • Do not chew the tablet and swallow it as a whole.
  • Take the right dose, not more or less.
  • Remember to take it at the same time and in the same way each day.
  • Drink plenty of fluids while having this medication to prevent kidney stones from forming. Doing so may lessen the risk of certain side effects.

What are the possible side effects of Topiramate?

  • Nausea
  • Loss of appetite
  • Changes in taste
  • Diarrhea
  • Nervousness
  • Dizziness
  • Difficulty concentrating
  • Mood problems
  • Weight gain
  • Drowsiness
  • Weakness
  • Insomnia

Some of these side effects are rare. It is important to call your doctor or seek medical assistance if there are any other side effects occur. If you experience signs of an allergic reaction, do not take any dose of this medicine and call for medical attention.

What are the precautions in taking Topiramate?

  • This medication may cause drowsiness and problems with concentrating and thinking clearly. If affected, do not drive or use any machinery that requires your alertness. Avoid drinking alcohol while having this drug as this is likely to make these problems worse.
  • This product should not be recommended for use in adolescents and young adults.
  • Inform your doctor if your condition does not improve or if it gets worse.
  • If you have a personal or family history of kidney stones, tell it right away to your doctor. This drug may increase the risk of kidney stones.
  • This should not be used to treat epilepsy in children less than two years of age. In children under 16 years old, this as well should not be used.
  • Let your doctor know if you have any medical history especially of kidney or liver problems, osteoporosis, ketogenic diet, and a certain metabolic imbalance.