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Where is Telaprevir used?

Telaprevir is an FDA-approved protease inhibitor medicine used in people with hepatitis C. This prescription may be used in people who have not yet received treatment for their hepatitis C or those whose disease has not improved with previous treatment. Telaprevir can be used along with Peginterferon Alfa and Ribavirin. 

How does Telaprevir work?

Telaprevir is an antiviral medication that works by preventing the protease enzyme from working. This drops the total hepatitis C virus in the body and leads to a decrease in liver damage and progress in liver function. 

Hepatitis C virus infects the liver and leads to liver damage. When the virus is inside the liver cells increases, it makes many replicas of its self. An enzyme made by the hepatitis C virus known as protease plays a vital role in this course. Protease disrupts up new proteins made by the virus so that new replicas of the virus can be accumulated from the pieces. If this enzyme is stopped from functioning, any new virus that is made is defective and incapable to infect more liver cells. 

How is Telaprevir taken?

  • This medicine should be taken with food. Each dose should be swallowed as a whole with water.
  • The usual dose is two tablets to be taken every 8 hours, 3 times each day or 3 tablets to be taken twice a day. You must always follow the instructions given by your doctor.
  • It is important to take the medicine with food and at consistent intervals so that effective levels of the drug are maintained in the blood.
  • This should be taken at the same time each day. If you usually take your medicine three times a day and you forget to take a dose, you should take the missed dose with food as soon as you remember. If your missed dose is more than four hours late, don’t take the missed dose. Just take your next dose at the usual time.
  • Do not exceed the recommended dosage given by your doctor. Take each dose exactly as it is prescribed. 

What are the possible side effects of Telaprevir?

  • Diarrhea
  • Vomiting
  • Nausea
  • Burning or discomfort around the anus
  • Dizziness
  • Pale skin
  • Dry mouth
  • Weakness
  • Increased thirst 
  • Tiredness
  • Dark-colored urine 

Telaprevir may cause other side effects. Let your doctor know if you have any rare problems while taking this medicine.

What are the precautions in taking Telaprevir?

  • This drug may affect vision in some people. You should take care when doing potentially dangerous activities such as operating machinery or driving until you know how this drug affects you.
  • The safety and effectiveness of this drug have not been established in people who have had a liver transplant or other organ transplant.
  • Stop using this medication and tell your doctor or pharmacist right away if you feel you have experienced an allergic reaction.
  • It is not known if this medication passes into breast milk. Nevertheless, this could be harmful to a nursing infant. Women needing treatment with this medication should not breastfeed. Breastfeeding must be stopped before treatment is started. Seek out further medical guidance from your doctor.