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Mafenide Acetate

Mafenide Acetate

What condition does Mafenide Acetate treat?

Patients with severe burns may use Mafenide Acetate for wound healing and infection prevention. Mafenide Acetate may be prescribed alone or in combination with other medications. This medication helps to promote wound healing by killing bacteria. The bacteria are also less likely to spread to the surrounding skin or blood. As a result, this prevents sepsis, a deadly blood infection.

Mafenide Acetate is an antimicrobial agent designated chemically as a-amino-p- toluenesulfonamide monoacetate. This comes as a cream for topical use. The Food and Drug Administration (FDA) has already approved this prescription.

How does Mafenide Acetate work?

Mafenide Acetate is a synthetic sulfonamide antibiotic. This works by killing bacteria that may affect an open wound. This also decreases the bacterial population present in the avascular tissues of burns. Mafenide Acetate permits spontaneous healing of deep partial-thickness burns.  

What is the recommended dosage for Mafenide Acetate?

The recommended dosage is based on your medical condition and response. Do not take more or less than it is given by your doctor. This medication is to be used on the skin only.

Wash your hands before and after using this medication. After cleaning the affected area, apply an exact amount of cream to the wound. Apply it while wearing a medical glove. This is usually applied once or twice a day or as directed by your doctor. The wound should be covered with this medication at all times. If some of the creams rub off the wound, re-apply it right away. Let your doctor know if your condition does not improve or if it gets worse. Do not suddenly stop using this prescription without the consent of your doctor. If you missed a day of using this cream, call your health care provider for instructions.

What are the side effects of Mafenide Acetate?

  • Burning or pain of treated skin
  • Redness, itching, rash, or blistering of treated skin
  • The white or pruned appearance of treated skin
  • Rapid breathing
  • Severe skin irritation
  • Dark-colored urine
  • Pale or yellowed skin

What are the precautions in taking Mafenide Acetate?

  • Tell your doctor if you are allergic to this medication.
  • Inform your doctor if you have any medical history or current medication.
  • Burned areas should be covered with cream at all times. Reapply whenever necessary if the cream is removed from any area.
  • Do not share this or any of your prescriptions with others even if they have the same symptoms as yours.
  • This medication may not be prescribed during pregnancy.
  • Consult your doctor first if you are breastfeeding women.
  • To help clear up your burn or skin infection completely, keep using this medication for full-time treatment. You must keep using the cream until the burn area is ready for skin grafting or has healed. You should not miss any doses.
  • The use of this medicine is not recommended in newborn infants up to 2 months old. Sulfa medications may cause liver problems in these infants.
  • Keep this at room temperature away from heat or moisture.