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Lopinavir and Ritonavir

Lopinavir and Ritonavir

General Information

Lopinavir and Ritonavir are used with another medication to help control HIV infection. This helps to lessen the amount of HIV in your body so your immune system can work better. This lowers your chance of getting HIV complications and improves your quality of life.

How do Lopinavir and Ritonavir work?

During infection with HIV, the virus multiplies within the body’s cells. Viruses are released from the cells and spread throughout the body where they infect other cells. In this manner, the infection is perpetuated among new cells that the body creates continually. During the production of the viruses, new proteins for the viruses are made. Some of the proteins are a structural protein that forms the body of the viruses. Other proteins are enzymes that manufacture DNA and other components for the new viruses. It is the protease that forms the new structural proteins and enzymes.

Lopinavir and Ritonavir block the action of protease. That it results in the formation of defective viruses that are unable to infect the body’s cell. Therefore, the number of viruses in the body decreases.

Why use Lopinavir and Ritonavir?

Lopinavir and Ritonavir are in the class of medications called protease inhibitors. The brand name of this product is Kaletra with its active ingredients Lopinavir and Ritonavir. This is available as a capsule with the strengths of 133.3 mg Lopinavir and 33.3 Ritonavir for oral use. The Food and Drug Administration (FDA) has already approved this prescription in 2000.

How to use Lopinavir and Ritonavir?

This medication is to be taken by mouth usually once or twice a day. You may take it with food or without food. Swallow the capsule as a whole. Do not chew or open it. Remember to take it at the same time every day.

The dosage is based on your medical condition and response to it. It is important to take it exactly as it is prescribed. Do not take more or less than the prescription. For the best benefit from it, take it regularly.

What are the side effects of Lopinavir and Ritonavir?

  • Headache
  • Diarrhea
  • Vomiting
  • Nausea
  • Drowsiness
  • Stomach upset
  • Weakness
  • Skin rash
  • Trouble sleeping
  • A bad taste in your mouth
  • Joint pain
  • Vision changes
  • Weight loss

Warnings and Precautions

  • Before taking this medicine, tell your doctor if you are allergic to it or if you have any allergies.
  • You should not share this drug with others even if they have the same symptoms as yours.
  • If you are breastfeeding women, consult your doctor first. This may not be recommended for pregnant women.
  • Let your doctor know if your condition does not improve or if it gets worse.
  • Before taking it, tell your doctor if you have any medical history.