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Firmagon (Degarelix) Injection

Firmagon (Degarelix) Injection

Degarelix General Information

Firmagon (Degarelix) Injection is indicated for the treatment of advanced prostate cancer. This condition can spread to any part of the body.  But it is commonly spreading to the bones and lymph nodes.

This medication is not a cure but this may help to slow the growth of cancer cells. Most types of prostate cancer need the male hormone testosterone to spread and grow.

How does Firmagon (Degarelix) Injection work?

Firmagon (Degarelix) competitively inhibits GnRH receptors in the pituitary gland. It prevents the release of luteinizing hormone (LH). It also prevents the release of follicle-stimulating hormones. Reduced LH suppresses testosterone release. It slows the development and lessens the size of prostate cancers.

Why use Firmagon (Degarelix) Injection?

Firmagon is a sterile lyophilized powder for injection. It contains Degarelix as an active ingredient. It is a synthetic linear decapeptide amide that has seven unnatural amino acids. This comes as 80 mg and 120 mg vial for subcutaneous administration. The Food and Drug Administration (FDA) has approved this medication.

How to use the Firmagon (Degarelix) Injection?

Firmagon Injection comes as a powder to be mixed with liquid. It is to be injected under the skin in the stomach area. It must be away from the ribs and waistline. This medication is usually injected once every 28 days.

The first dose is given as two injections. The following doses are given as one injection.  To help you remember, mark your calendar to keep track of when to schedule the next dose.

What are the side-effects of Firmagon (Degarelix) Injection?

Common side effects:

  • Chills
  • Back or joint pain
  • Fatigue
  • Tiredness
  • Dizziness
  • Fever
  • Nausea
  • Weakness
  • Insomnia
  • Headache
  • Increased sweating
  • Weight gain
  • Constipation
  • Injection site reactions (redness, swelling or pain)

If these side effects continue or get worse, call your doctor right away.

Warnings and Precautions

  • While having this treatment, makes sure the injection site is free from any pressure. It is more likely pressure from belts, waistbands, or other types of clothing.
  • Change the injection site each time to lessen the discomfort after the injection.
  • Call for medical help if there are signs of an allergic reaction.
  • This is not usually used in women. You should also not use this in pregnant or breastfeeding women.
  • Before having this medication, tell your doctor if you are taking other medications.
  • This drug may make you feel dizzy. Do not drive or use any machinery.