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Daraprim (Pyrimethamine)

Daraprim (Pyrimethamine)

Pyrimethamine General Information

Daraprim (Pyrimethamine) is for the treatment of serious parasite infection or called toxoplasmosis of the body, eye, or brain. This may also be used to prevent toxoplasmosis infection in people with HIV infection. This is used along with other medications like sulfonamide to treat such a condition. 

How does Daraprim (Pyrimethamine) work?

Daraprim (Pyrimethamine) is used for treating plasmodia infections and Toxoplasma gondii. Toxoplasma gondii is a parasite that causes toxoplasmosis and plasmodia parasites causes’ malaria. This medication inhibits parasites from making important proteins. It is by blocking the use of folic acid which is needed for the creation of proteins. Preventing parasites from producing important proteins prevents the growth and progress of new parasites. 

Why use Daraprim (Pyrimethamine)?

Daraprim (Pyrimethamine) is an anti-parasite medicine that helps prevent parasites from developing and reproducing in the body. This was originally approved in the year 1953 by the Food and Drug Administration (FDA). Daraprim is available as tablets for oral administration that contains 25mg of Pyrimethamine. 

How to use Daraprim (Pyrimethamine)?

Daraprim (Pyrimethamine) is usually taken once or twice daily. Take the tablet with food to decrease nausea and vomiting. If vomiting is severe, your doctor may lower your dose or direct you to stop taking the medication. Drink plenty of water to prevent kidney problems if you are taking a ‘sulfa’ medication with Daraprim. Take it at the same time each day. The recommended dosage is based on your condition and response to it. Follow the prescription of your doctor very carefully. Do not double the given dosage to avoid some complications. 

What are the side-effects of Daraprim (Pyrimethamine)?

Common side effects:

  • Vomiting
  • Loss of appetite
  • Nausea
  • Headache
  • Insomnia
  • Dry mouth
  • Light-headedness

Call your doctor right away if these happen:

  • Pale skin, purple spots under your skin, easy bruising
  • Sore throat, swelling in your tongue
  • Blood in your urine
  • The first sign of any skin rash, no matter how wild
  • Fever, flu or cold symptoms
  • Irregular heartbeats
  • New or worsening cough, fever, trouble breathing

Warnings and Precautions

  • Tell your doctor if you have any allergies or if you are allergic to this medicine. Tell also to your doctor if you have any medical history or current medications (vitamins or herbal supplements)
  • Talk to your doctor first if you are pregnant or breastfeeding women before taking this drug.
  • You should not share this or any of your medications even if you have the same symptoms.
  • Keep this far from the reach of children or pets.