Daliresp (Roflumilast)

April 01, 2019

Medicine

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Roflumilast General Information

Daliresp (Roflumilast) is used to control and prevent symptoms of wheezing and shortness of breath. In which, it is caused by on-going lung disease or a chronic obstructive pulmonary disease-COPD which includes bronchitis. This should be used along with medications like bronchodilators (salmeterol or ipratropium) to treat COPD. Controlling the symptoms of breathing problems can decrease time lost from work or school. 

How does Daliresp (Roflumilast) work?

The active ingredient of Daliresp is Roflumilast. It is a PDE4 inhibitor that blocks the action of PDE4. PDE4 is an enzyme that plays a critical part in some pathways in the body. It includes the pathways that affect the inflammatory response and the immune system. It also impacts smooth muscle relaxation in the body, including smooth muscle relaxation in the airways. By blocking PDE4, this drug acts as anti-inflammatory medication, as well as a smooth muscle relaxant. Inflammation and bronchoconstriction or the tightening of the muscles in the airway both play key roles in the exacerbation and development of COPD. By inhibiting these processes, a PDE4 medication, like Daliresp, may be able to reduce COPD symptoms and exacerbations for those taking it.

Why use Daliresp (Roflumilast)?

Daliresp (Roflumilast) is a selective phosphodiesterase 4 (PDE4) inhibitors. It is supplied as white to off-white round tablets. Each tablet contains 250mcg or 500mcg of Roflumilast for oral administration. This has been approved by the Food and Drug Administration (FDA). 

How to use Daliresp (Roflumilast)?

The recommended dosage for this medication is based on your condition and response.

The usual dose of this is one 500mcg tablet once a day. It is also common for some to take 250mcg once daily for the first four weeks of the treatment. After that, your doctor may increase your dose to 500mcg. You may take the medicine with or without food.

Follow your doctor’s prescription very carefully. Take it at the same time each day.

What are the side-effects of Daliresp (Roflumilast)?

• Nausea
• Diarrhea
• Abdominal or stomach pain
• Loss of appetite
• Headache
• Minor weight loss
• Runny or stuffy nose
• Dizziness
• Flu symptoms
• Back pain
• Acute renal failure and acute pancreatitis

Let your doctor know if you these side effects:

• Trouble sleeping
• Mood/mental changes
• Fast or irregular heartbeat
• Shaking or tremors

Warnings and Precautions

• Before taking this treatment, inform your doctor if you have any allergies.
• This is only prescribed in pregnant women when clearly needed. Consult your doctor if you are breastfeeding women.
• Keep this away from the reach of children.