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Clobazam is a prescription used to treat epilepsy in adults and children over six years of age. This is used in combination with other antiepileptic medicines. It is to help prevent various types of epileptic attacks. Epilepsy is a central nervous system disorder. In which the brain activity becomes abnormal that causes periods of unusual behavior, sensation, and sometimes loss of awareness. Because epilepsy is caused by abnormal activity in the brain, it can affect any process your brain coordinates. Seizure signs and symptoms may include:
- A staring spell
- Temporary confusion
- Uncontrollable jerking movements of the arms and legs
- Psychic symptoms such as anxiety and fear
This medication may also be used for the short-term treatment of severe anxiety in adults. Wherein, it is disabling or causing the individual to unacceptable distress. Experiencing occasional anxiety is a normal part of life. Yet, people with anxiety disorders frequently have excessive, intense, and persistent worry and fear. Sometimes, this type of disorder involves repeated episodes of sudden feelings of intense anxiety and fear or panic attacks. Common anxiety signs and symptoms:
- Feeling weak or tired
- Having trouble sleeping
- Having difficulty controlling worry
- Feeling nervous, tense or restless
- Having a sense of impending danger, doom or panic
Clobazam is a type of medicine called benzodiazepine. Benzodiazepines are used for their sedative, anxiety-relieving, and muscle-relaxing effects. This type of drugs acts on nerve cells in the brain. This product is supplied as tablets for oral use. Each tablet contains Clobazam as an active ingredient. It is a white or almost white crystalline powder with a slightly bitter taste. It is also slightly soluble in water and sparingly soluble in ethanol. This is available in the dosage form of 10 mg and 20 mg. The Food and Drug Administration (FDA) has already approved this medication.
How does Clobazam work?
The brain and nerves are made up of many nerve cells. Through electrical signals, it communicates with each other. These signals must be carefully regulated for the brain and nerves to function properly. When abnormally rapid and repetitive signals released in the brain, it becomes over-stimulated and normal function is disturbed. This results in fits or seizures. Anxiety may also be related to the inappropriate stimulation of nerve cells in the brain.
This drug works by acting on receptors in the brain called GABA receptors. This causes the release of a neurotransmitter called GABA in the brain. Neurotransmitters are chemicals that are stored in nerve cells in the brain and nervous system. These are also involved in transmitting messages between the nerve cells. GABA is a neurotransmitter that acts as a natural ‘nerve-calming’ agent. It helps keep the nerve activity in the brain in balance. It is also involved in inducing sleepiness, decreasing anxiety, and relaxing muscles.
As Clobazam increases the activity of GABA in the brain, it also increases its calming effects. By calming nerve cells, this drug prevents excessively rapid and repetitive firing of electrical signals. This stabilizes the electrical nerve activity in the brain that helps to prevent fits. Its calming effects allow it to be used for the short-term treatment of severe anxiety. This will also help with associated sleeping problems.
How to use Clobazam?
The recommended dosage is based on your medical condition, age, and response to the treatment. You must take this prescription exactly as it is given by your doctor. Don’t forget to take it at the same time and in the same way each day. For the best benefit from this drug, use this regularly. Do not take more often or less than the given length of time from your doctor.
Clobazam is usually taken once or twice a day by mouth. You may take each dose with or without food or as directed by your doctor. If you are taking this drug once daily, take it at bedtime. If you are taking it in divided doses, take the larger dose at bedtime. Swallow the tablet as a whole with a full glass of water. Do not chew or crush the tablet. Do not suddenly stop taking this medicine without the consent of your doctor. It may worsen your condition or may cause another complication.
What are the side effects of Clobazam?
Common side effects:
- Feeling tired
- Aggressive behavior
- Breathing problems
- Slurred speech
- Sleep problems or insomnia
- Painful urination
Call your doctor right away if you have:
- Severe drowsiness or feeling like you might pass out
- Weak or shallow breathing
- Urinating less than usual or not at all
- Pain or burning when you urinate
- Fever, chills, or cough with yellow or green mucus
Get emergency medical help if you have signs of an allergic reaction:
- Trouble breathing
- Swelling of your lips, face, tongue, and throat
Warnings and Precautions
- Do not take this medication if you are allergic to it. This drug may contain some ingredients that cause an allergic reaction.
- Before taking, let your doctor know if you have ever had muscle disorders, liver disease, or glaucoma.
- This drug may make you dizzy or drowsy. Do not use any machinery or do anything that needs your alertness.
- While having this treatment, avoid alcoholic beverages. Alcohol may increase drug levels.
- This should only be used when needed during pregnancy. If you are breastfeeding women, consult your doctor first before taking a dose.
- Report any new or worsening symptoms to your doctor such as panic attacks, mood or behavior changes, trouble sleeping, or have thoughts about suicide or hurting yourself.
- This prescription should not be given to a child younger than 2 years old.
- If you missed a dose, take it as soon as you remember it. If it is almost time for your next dose, skip the missed dose and continue your regular dosing schedule.
- Tell your doctor if you have any other medications such as vitamins or herbal supplements.
- Do not share this or any of your medications with others even if they have the same symptoms as yours.