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Cetirizine Hydrochloride

Formula Drugs

Cetirizine Hydrochloride is used for the treatment of allergies such as seasonal and perennial allergic rhinitis.

Allergies are an exaggerated immune reaction to normally harmless substances known as allergens. When a susceptible person is first exposed to an allergen, an immune response is activated. There are two types of allergic rhinitis; seasonal and perennial. Seasonal occurs at specific times of the year which is a reaction to airborne allergens (ragweed, tree and grass pollen). Perennial occurs year-round usually a reaction to indoor allergens such as mold, pet dander, or dust mites. Some of the symptoms of allergy may include:

  • Sneezing
  • Runny nose with clear discharge
  • Nasal or sinus congestion
  • Itchy nose
  • Postnasal drip
  • Headache
  • Itchy, red, or watery eyes
  • Cough
  • Difficulty breathing or wheezing
  • Red or inflamed skin

This medication can also be used to treat hives. Hives are itchy and red welts that result from a skin reaction. The welts appear and fade repeatedly as the reaction runs its course. The condition is considered chronic hives if the welts appear for more than six weeks. It may recur frequently over months or years. Hives can be very uncomfortable and interfere with sleep and daily activities. Some signs and symptoms of hives may include:

  • Itching
  • Bumps that vary in size
  • Batches of red or skin-colored welts which can appear anywhere in the body
  • Painful swelling of the lips, eyelids, and inside the throat

Cetirizine Hydrochloride belongs to the family of medicines called antihistamines. This blocks a certain natural substance that your body makes during an allergic reaction. This helps relieve allergy symptoms. The U.S. Food and Drug Administration (FDA) has already approved this medication. Cetirizine Hydrochloride comes as a sterile, colorless, clear, non-pyrogenic, and isotonic solution for intravenous injection. Each contains Cetirizine Hydrochloride as an active ingredient. This is available in the dosage form of 10 mg/mL.

How does Cetirizine Hydrochloride work?

Cetirizine Hydrochloride works by preventing the actions of histamine. It is a substance produced by the body when it reacts to a foreign substance such as pollen or pet fur. Histamine acts on histamine receptors causing a chain reaction that result in allergic symptoms. In allergic reactions like hay fever, histamine causes inflammation of the nose, eyes or airways. That it results in itchy, watery eyes, a runny, blocked or itchy nose and sneezing. In allergic skin reactions, histamine causes skin inflammation, rashes, and itching.

This medication blocks histamine receptors and so stops the chain reaction that causes the symptoms of the allergy. It usually starts to work within half an hour to an hour after taking a dose.

How to use Cetirizine Hydrochloride?

The dosage will depend on your medical condition, age, and response to the medication. Before using this product, check it visually for particles or discoloration. If either is present, do not use the liquid. Clean the injection site with rubbing alcohol before injecting each dose. Learn how to store and discard medical supplies safely. To get the most benefit from it, use the medication regularly. Remember to use the prescription at the same time each day.

Cetirizine Hydrochloride is given by injection intravenously. This is usually given as directed by your doctor. Your doctor may start at a low dose and gradually increase it. You must take this medication exactly as it is prescribed. Do not take more or less than it is given by your doctor. If you missed a dose, take it as soon as you remember it. If it is almost time for your next dose, skip the missed dose and follow your regular schedule. Do not double the dose to make up for the missed dose. Tell your doctor if your allergy symptoms do not improve, if your hives do not improve after 3 days of treatment, and if it lasts for more than 6 weeks. Call for medical help right away if your condition gets worse or if you think you have a serious medical problem.

What are the side effects of Cetirizine Hydrochloride?

Common side effects:

  • Headache
  • Changes in taste
  • Light-headedness
  • Numbness and tingling
  • Feeling hot
  • Indigestion
  • Increased sweating
  • Fatigue
  • Drowsiness
  • Dizziness
  • Sore throat
  • Excessive tiredness
  • Stomach pain
  • Vomiting
  • Diarrhea
  • Dry mouth

Tell your doctor right away if you have any serious side effects such as:

  • Weakness
  • Difficulty urinating
  • Constipation

A very serious allergic reaction to this drug is rare. However, call for a medical emergency if you notice any symptoms of a serious allergic reaction such as:

  • Swelling of the face, lips, throat, and tongue
  • Trouble breathing
  • Rash or itching

Warnings and Precautions

  • Before taking Cetirizine Hydrochloride, let your doctor know if you ever had an allergic reaction to this. This drug may contain an inactive ingredient that causes an allergic reaction.
  • Inform your doctor if you ever had any medical history especially of difficulty urinating, liver or kidney disease.
  • This drug may make you drowsy. Alcohol can make you dizzier. Do not drive or do any activity that requires your alertness. Limit alcoholic beverages.
  • Do not share this with others even if they have the same sickness as yours.
  • Tell your doctor if you are pregnant or planning to become pregnant. Cetirizine Hydrochloride should be used during pregnancy if only needed. If you become pregnant while taking this medication, call your doctor right away.
  • For women who are breastfeeding, you need to talk to your doctor first for some instructions.
  • This product can be taken by adults and children aged 2 years and over. This should not be given in children under 2 years of age.
  • A lower dose may be needed in people with kidney problems. Dosage should also be monitored in people who suffer from epilepsy or are at risk of convulsions.
  • Do not use this for the treatment of any other diseases without the consent of a doctor.
  • Check with your doctor before taking any other medications. This includes vitamins or herbal supplements.
  • Keep the medicine away from heat and direct sunlight. Make sure that children cannot see or reach it.