Cerezyme (Imiglucerase) for Injection

June 11, 2019

Medicine

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Imiglucerase General Information

Cerezyme (Imiglucerase) for Injection is indicated to treat a certain rare genetic problem. It is called Gaucher disease. It is a genetic disorder in which the body lacks the enzyme needed to break down certain fatty materials. It is called lipids that can build up in the body that causes symptoms such as:

• Anemia
• Easy bruising or bleeding
• Bone or joint pain
• Weakness
• Enlarged liver or spleen
• Weakened bones that are easily fractured

This medication improves bone, blood, and liver spleen problems. This does not correct the genetic problem and treatment must continue for life.

How does Cerezyme (Imiglucerase) work?

Cerezyme (Imiglucerase) for Injection works inside the lysosome. It is a specialized compartment of the cell where the breakdown of glucocerebroside usually happens. Glucocerebroside is broken down into glucose and ceramide. This can be then removed from the cell by natural processes.

Why use Cerezyme (Imiglucerase)?

Cerezyme (Imiglucerase) replaces a certain natural substance that is missing in people with Gaucher’s disease. Those natural substances are enzymes called glucocerebrosidase. This product is supplied as a sterile, non-pyrogenic, and white to off-white lyophilized. The Food and Drug Administration (FDA) has already approved this medicine.

How to use Cerezyme (Imiglucerase)?

Cerezyme (Imiglucerase) for Injection is given by intravenous infusion. It is delivered directly into your bloodstream. This medication typically takes 1-2 hours. It is usually given every two weeks.

The recommended dosage is based on your medical condition and response to it. It is important to take it exactly as it is prescribed. Before using this medicine, check this product visually for particles or discoloration. If it is present, do not use it anymore.

What are the side-effects of Cerezyme (Imiglucerase)?

• Vomiting
• Nausea
• Abdominal pain
• Diarrhea
• Headache
• Fatigue
• Dizziness
• Rash
• Injection site reactions (burning, itching, discomfort, open wound or sore)

Warnings and Precautions

• Before taking each dose, tell your doctor if you are allergic to it. This drug may contain an inactive ingredient that causes an allergic reaction.
• If you are pregnant or breastfeeding women, consult your doctor first before taking this drug.
• Do not use this drug past the expiration date.
• Let your doctor know if your condition persists or worsens.  
• You should not share this prescription with others even if they have the same symptoms as yours.
• Inform your doctor if you have a medical history or current medications.
• Keep this away from the reach of children.