Basiliximab (Simulect) for Injection

March 06, 2019

Medicine

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General Information

Basiliximab (Simulect) for Injection is used to prevent organ rejection. It is for those who have received a kidney transplant. This is usually taken along with other medications like corticosteroids or cyclosporine. These treatments allow your new organ to function normally.

How does Basiliximab (Simulect) for Injection work?

Basiliximab (Simulect) for Injection lessens the body’s immune response. The immune system usually protects the body from infections and foreign cells. It is by making antibodies to fight them. A transplanted organ can be attacked by the immune system in a similar way. It is known by the body as a foreign substance. This is known as “transplant rejection”.

Basiliximab is used in kidney transplants to block this immune response. This is intended to know and bind to the receptors displayed by the activated T-cells. This blocks interleukin-2 from binding to the T-cells and stimulating them to grow. The outcome is to protect the transplanted kidney from being attacked by large numbers of T-cells, which gives the transplant a greater chance of being successful.

Why use Basiliximab (Simulect) for Injection?

Basiliximab (Simulect) for Injection is a type of medicine called a monoclonal antibody. It belongs to a group of medicines known as immunosuppressants. This medication slows down your body’s defense system to prevent rejection after the surgery. This has been already approved by the Food and Drug Administration (FDA).

How to use Basiliximab (Simulect) for Injection?

This treatment is given by injection. This is to be injected into a vein by your doctor or healthcare professional. This is usually given in 2 doses. The first is within 2 hours before the surgery. The second is given 4 days after the surgery. The dosage will depend on your condition, weight, age, and response. Take all your medications exactly as it is directed by your doctor.

What are the side-effects of Basiliximab (Simulect) for Injection?    

• Constipation
• Diarrhea
• Stomach pain
• Nausea
• Acne
• Sleep problems
• Headache
• Cold symptoms (sore throat, stuffy nose)
• Swelling in your hands, feet, or ankles
• Redness or pain at the injection site
• Trouble breathing
• Pain or burning when you urinate

Warnings and Precautions

• This medication should be used only when clearly needed during pregnancy.
• Inform your doctor if you have any allergies or medical history.
• If you missed a dose, call your doctor right away for instruction.
• Do not stop this medication without consulting your doctor.
• Keep this far from the reach of children.