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Zortress (Everolimus) is used to prevent rejection of a kidney transplant. This is also used with other medications to prevent rejection of a liver transplant. This is used in adult patients at low-moderate immunologic risk receiving a kidney transplant.
How does Zortress (Everolimus) work?
Zortress (Everolimus) lowers your body’s immune system. Your body fights infection through the help of your immune system. It can also ‘reject’ or fight a transplanted organ such as a liver or kidney. This is because the immune system treats the new organ as an invader.
This medication binds to the immunophilin FK Binding Protein-12to generate an immunosuppressive complex. It binds and inhibits the activation of the mammalian Target of Rapamycin. It is a key regulatory kinase. Inhibition of it results in the inhibition of T lymphocyte activation and inhibition of antibody production. It also results in proliferation associated with antigen and cytokine stimulation.
Why use Zortress (Everolimus)?
Zortress (Everolimus) belong to the class of drugs known as immunosuppressants. This comes as a tablet for oral administration. This drug has Everolimus as an active ingredient. Each tablet contains 0.25 mg, 0.5 mg, and 0.75 mg. The Food and Drug Administration (FDA) has already approved this medication.
How to use Zortress (Everolimus)?
This is to be taken by mouth with a full glass of water. It is usually taken every 12 hours. This medication is usually started 30 days after a liver transplant. You may take it with or without food. Swallow the drug as a whole. Do not break or chew the tablets. To help you remember, take it at the same time each day. The dosage is based on your medical condition and response.
What are the side-effects of Zortress (Everolimus)?
- Sores in the mouth or throat
- Swelling in your legs, ankles, or feet
- Insomnia (sleep problems)
Warnings and Precautions
- Before taking this drug, tell your doctor if you have any allergies. This may have an inactive ingredient that causes an allergic reaction. Tell also to your doctor if you have any medical history or current medications.
- Do not have vaccinations/immunizations without the consent of your doctor.
- This drug may increase your risk of developing skin cancer. Limit your time in the sun.
- Do not use this past the expiration date.
- You should not share this with others who have the same symptoms as yours.
- Keep this away from the heat and moisture.