Sacrosidase

January 08, 2020

Medicine

formuladrugs.com

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Sacrosidaseis a prescription used in a certain condition such as congenitalsucrose-isomaltase deficiency (CSID). This drug is used to replace the sucroseenzyme in your body. It helps to digest and absorb sucrose or sugar. Sucrosehelps the body breakdown and processes certain sugars during digestion. Inpeople who lack the sucrase enzyme, sugar can pass into the intestines where itcan interact with bacteria. 

CSID is agenetic condition that affects a persons’ ability to digest certain sugars.People with this condition cannot break down the sugars sucrose. CSID usuallybecomes superficial after an infant begins to consume juices, fruits, andgrains. After ingestion of sucrose, an affected child will typically experiencebloating, stomach cramps, and excess gas production. After ingestion ofsucrose, an affected person will typically experience:

• Watery diarrhea
• Bloating
• Excess gas production
• Abdominal pain
• Mal-absorption of another nutrient
• Nausea
• Vomiting
• Reflux-like symptoms

In somechildren, these digestive problems can lead to failure to gain weight and growat the expected rate and malnutrition. As they get older, most affectedchildren are better able to tolerate maltose and sucrose. Symptoms can vary fora variety of reasons including the timing of introduction of sucrose into aperson’s diet, and the amount of sugar and starch consumed.

Importanceof sucrose 

Your bodyrequires a constant supply of energy. As a carbohydrate, sucrose provides yourbody with the energy required to perform physical and mental functions. Yourbody breaks down foods such as sucrose and starch into fructose and glucoseduring digestion. The fructose and glucose are metabolized by your body torelease energy to your cells. The energy produced during metabolism helps yourbody carry out both physical and mental activities. 

Sacrosidaseis a product approved by the Food and Drug Administration (FDA). This isavailable in 118 mL translucent plastic bottles. Each mL solution contains8,500 I.U. of Sacrosidase. 

How doesSacrosidase work?

Sacrosidasehelps improve the breakdown and absorption of sucrose from the intestine. Thisalso helps relieve the gastrointestinal symptoms of CSID. Sacrosidase does notbreak down some sugars resulting from the digestion of starch. Therefore, youmay need to restrict the amount of starch in your diet. Your doctor will tellyou if you should restrict the amount of starch in your diet. 

This drugis a replacement remedy for the treatment of the genetically determined sucrasedeficiency that is part of CSID. Sucrase is certainly made in the brushboundary of the small intestine. Primarily, it is the distal jejunum andduodenum. Sucrase hydrolyzes the disaccharide sucrose into its componentmonosaccharides, fructose, and glucose. Isomaltase breaks down disaccharidesfrom starch into simple sugars. Sacrosidase does not containisomaltase.  

How touse Sacrosidase?

Sacrosidaseis usually taken with each meal or snack. It is best to take one half of thedose when you start eating. During your meal or snack, you may take the otherhalf. 

Take thismedication exactly as prescribed by your doctor. Do not take it in largeramounts or for longer than recommended. Follow the directions on yourprescription label. Measure your dose using the scoop provided withSacrosidase. Rinse the scoop after each use and allow it to dry thoroughly.Sacrosidase liquid should be mixed with 2 to 4 ounces of milk or water. Do notmix with warm or hot liquids or the medication will not be as effective. Do notas well mix Sacrosidase with fruit juice or drink fruit juice when taking themedication. 

Beforeyou start the medication, your doctor may recommend a Sacrosidase skin test tomake sure you are not allergic to the medication. This medication sometimescauses an allergic reaction. Your doctor may instruct you to take your firstdose of Sacrosidase in a place where you have access to emergency medical care.A severe allergic reaction could occur that may require immediate care.

What arethe side effects of Sacrosidase?

Commonside effects:

• Nausea
• Stomach pain
• Diarrhea
• Vomiting
• Sleep problems or insomnia
• Constipation
• Nervousness
• Headache
• Dry or hot skin
• Increased thirst 

Call yourdoctor right away if you have these side effects:

• Feeling thirsty or hot
• Being unable to urinate
• Heavy sweating 

Getemergency medical help if you have any of these signs of an allergic reaction:

• Difficult breathing
• Hives
• Swelling of your lips, face, tongue, orthroat 

This isnot the complete list of the side effects. Call your doctor if there are sideeffects happened. 

Warningsand Precautions

• If you missed a dose, call your doctor forinstructions. Do not take extra medicine to make up the missed dose. 
• You may need to avoid eating a lot of starch. It ismainly found in potatoes, rice, pasta, corn, and bread. Follow your doctor’sinstructions about any special diet while you are taking this medicine. 
• There may be other medications that can interactwith Sacrosidase. Tell your doctor about all your prescription andover-the-counter medications, minerals, herbal products, vitamins, and drugsprescribed by other doctors. Do not begin with new medication without tellingyour doctor.
• Always consult your healthcare provider to ensurethe information displayed on this page applies to your circumstances.
• Let your doctor know if you ever had an allergicreaction to this medication. Tell as well if you have any allergies. Thisproduct may contain an inactive ingredient that causes an allergicreaction. 
• You should not take Sacrosidase if you are allergicto yeast, glycerine, yeast products, or papain. 
• To make sure Sacrosidase is safe for you, tell yourdoctor if you have diabetes. Sacrosidase changes the way your body absorbssugar and your glucose levels may change. Your doctor will tell you if any ofyour medication doses need to be changed.
• Tell your doctor if you are breastfeeding whiletaking Sacrosidase.
• If you are pregnant, consult your doctor firstbefore taking this drug. It is not known yet whether Sacrosidase will harm anunborn baby. 
• Keep this and all other medicines out of the reachof children. Never share your medicines with others and use this drug only forthe indication prescribed.