Promethazine Hydrochloride

October 18, 2019

Medicine

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Promethazine Hydrochloride is usedto:

• Relieve symptoms of allergic reactions such as hayfever, nettle rash, or insect bites and stings
• Prevents and treats sickness and  vomiting such as travel sickness or sicknessassociated with vertigo
• Short-term treatment for insomnia

Allergic reactions occur whenyour immune system reacts to a foreign substance. Your immune system produces substancesknown as antibodies. When you have allergies, your immune system makesantibodies that identify a particular allergen as harmful even though it isnot. The severity of allergies varies from person to person and can range fromminor irritation to anaphylaxis. Allergy symptoms can affect your airways,sinuses/nasal passages, skin, and digestive system.

Vertigo is a sensation ofspinning dizziness. It can happen when there is a problem with the inner ear, brain,or sensory nerve pathway. Vertigo can happen at any age but it is common in peopleaged 65 years and over. This condition can be temporary or long-term and may affecta person’s ability to function in daily life.

Insomnia is difficulty fallingasleep or staying asleep. This may be characterized based on its duration; acuteinsomnia often occurs because of life circumstances. Chronic insomnia is disruptedsleep that happens at least 3 nights per week and lasts at least 3 months. Peoplewith this disorder can feel dissatisfied with their sleep and usually experience:

• Low energy
• Fatigue
• Mood disturbances
• Difficulty concentrating
• Decreased performance at school or work

Promethazine Hydrochloride is atype of medicine called sedating antihistamine. This prevents the actions ofhistamine that your body makes during an allergic reaction. Its other effect isby affecting other natural substances and by acting directly on certain partsof the brain. This product is supplied as tablets for oral use. Each tablet is availablein the dosage strengths of 25 mg and 50 mg. The Food and Drug Administration (FDA)has already approved this prescription.

Howdoes Promethazine Hydrochloride work?

For allergies, Promethazine Hydrochlorideblocks histamine from binding to its receptors in various parts of the body. Histamineis a substance produced by the body as part of its defense mechanisms. This medicationstops it causing the symptoms of an allergic reaction.

For vertigo, this drug blockshistamine receptors in an area of the brain called the vomiting center. This partof the brain is activated when it gets nerve messages to form a part of theinner called the vestibular apparatus. It’s responsible for making you feelsick and for the vomiting reflex. Promethazine Hydrochloride stops the vomitingcenter from being activated.

For insomnia, this is known as asedating antihistamine because it enters the brain in significant quantities andmakes you feel sleepy. You can use this drug for a short period. It is to helpyou get to sleep if you are having trouble sleeping.

Howto use Promethazine Hydrochloride?

Promethazine Hydrochloride is tobe taken by mouth. The tablet is to be swallowed as a whole with a full glassof water. Do not break, chew, or crush the drug. For allergies, this is usuallytaken one to four times a day before meals at bedtime. For travel sickness, thisis taken 30 to 60 minutes before travel and taken again after 8 to 12 hours ifneeded. For longer trips, it is usually in the morning and before the evening mealon each day of travel. Drink plenty of fluids while having this treatment.Doing so may lessen the risk of certain side effects. The recommended dosage isbased on your medical condition, age, and response to the treatment. Yourdoctor may direct you to start at a lower dose and eventually increase it.

You should not take more or lessthan it is given. Even if you feel well, continue to take the medication untilthe full prescription is done. Do not suddenly stop taking Promethazine Hydrochloridewithout the consent of your doctor. If you missed a dose, take it as soon asyou remember it. If it is almost time for your next dose, skip the missed doseand continue your regular dosing schedule. Do not double the dose to make upfor the missed dose. Let your doctor know if your condition worsens or does notimprove.

Whatare the side effects of Promethazine Hydrochloride?

Common side effects:

• Dizziness
• Drowsiness
• Blurred vision
• Anxiety
• Stuffy nose
• Dry mouth
• Weight gain
• Ringing in your ears
• Impotence
• Swelling in your hands or feet
• Constipation
• Trouble having an orgasm

Stop using Promethazine Hydrochlorideand call your doctor right away if you have:

• A light-headed feeling like you might pass out
• Weak or shallow breathing
• Severe drowsiness
• Seizure
• Agitation
• Confusion
• Yellowing of the skin or eyes (jaundice)
• Easy bleeding or bruising
• Uncontrolled muscle movements in your face
• Sudden weakness or ill feeling, chills, fever, ormouth sores
• Sore throat or trouble swallowing
• Severe nervous system reaction (sweating, tremors,confusion, very stiff muscles, and high fever)

Warningsand Precautions

• Promethazine Hydrochloride should only be usedduring pregnancy if your doctor tells you to do so. This should not be used duringthe last two weeks of pregnancy. If taken during this time it may cause irritabilityor excitement in the baby after birth. If you get pregnant while taking this medicine,call your doctor right away.
• If you ever had an allergic reaction to thisproduct, let your doctor know before taking a dose. Tell as well to your doctorif you have any allergies.
• This is not recommended for use in children under twoyears of age.
• This should be used with caution in people who areover 65 years old, who have kidney or liver problems, and who have severe heartdisease.
• Before using Promethazine Hydrochloride, inform yourdoctor if you have any medical history especially of breathing problems, heartdisease, difficulty urinating, and high pressure in the eye.
• This may make you more sensitive to the sun. Limityour time in the sun. When outdoors, use sunscreen and wear protectiveclothing.
• While having this treatment, avoid alcoholic beverages.