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Zidovudine

Zidovudine is used in pregnantwomen to prevent passing the...

Prochlorperazine

Prochlorperazine

Prochlorperazine is aprescription used to treat nausea and vomiting. This used in a lower dose totreat the condition. This prescription may also be used for the treatment ofanxiety and a certain psychiatric illness called schizophrenia.

Nausea and vomiting are not adisease but rather, these are symptoms of many different conditions such as:

  • Motion sickness
  • Food poisoning
  • Brain injury
  • Migraines
  • Appendicitis

Sometimes, it can also besymptoms of more serious diseases. Nausea and vomiting differ from each other.Nausea is an uneasiness of the stomach that often accompanies the urge tovomit. Vomiting is the forcible voluntary or involuntary emptying or throwingup of stomach contents through the mouth. Nausea and vomiting may happen inboth children and adults.

Anxiety involves more thantemporary worry or fear. That it does not go away and can get worse over time. Thesymptoms of this condition can interfere with daily activities such as school,job, and relationships. Experiencing occasional anxiety is a normal part oflife. Symptoms may start during childhood or the teen years and continue intoadulthood.

Schizophrenia affects how aperson feels, thinks, and behaves. It can be a chronic or severe mentaldisorder. People with this illness may seem like they have lost touch withreality. Schizophrenia may result in some combination of delusions,hallucinations, and extremely disordered thinking.

Prochlorperazine is a type ofdrug known as a phenothiazine. This blocks dopamine receptors in the brain.Dopamine is a natural compound called a neurotransmitter that is involved intransmitting messages between brain cells. It is known to be involved inregulating mood and behavior. It also acts in an area of the brain thatcontrols nausea and vomiting. This is a prescription approved by the Food andDrug Administration (FDA). This product comes as a tablet for oral use. Eachtablet is available in the dosage forms of 5 mg and 10 mg with an activeingredient of Prochlorperazine.

Howdoes Prochlorperazine work?

In nausea and vomiting, Prochlorperazineblocks dopamine receptors found in the chemoreceptor trigger zone (CTZ). Wherein,it stops it from sending the messages to the vomiting center that causes nauseaand vomiting. Vomiting is controlled by an area of the brain called thevomiting center. The vomiting center is responsible for causing feelings ofsickness and for the vomiting reflex. It activates when receives nerve messagesfrom another area of the brain called CTZ and when it receives nerve messages fromthe gut.

In psychiatric illness, thismedicine is sometimes described as a neuroleptic or a major tranquilizer. Ithas a calming effect on people suffering from anxiety. Schizophrenia is thoughtto be caused by the overactivity of dopamine in the brain. By blocking dopaminereceptors, Prochlorperazine decreases the action of dopamine in the brain andit helps control psychotic symptoms.

Howto use Prochlorperazine?

The prescribed dosage is based onyour medical condition, age, and response to it. Your doctor may direct you tostart at a lower dose and eventually increase it. Prochlorperazine is to betaken by mouth with a full glass of water. Drink plenty of fluids while havingthis treatment. Doing so may lessen the risk of certain side effects. It isusually taken 3 to 4 times a day or as directed by your doctor. You may takeeach dose with or without a meal. Swallow the tablet as a whole. Do not break,chew, or crush it. You must take this medication exactly as it is given by yourdoctor. You should not take less or more often than the prescription.

To help you remember, take it atthe same time and in the same way each day. Take it regularly for the bestresult from this product. If you missed a dose, take it as soon as you rememberit. If it is almost time for your next dose, skip the missed dose and continueyour regular dosing schedule. Do not double the doses to make up for the misseddose. Do not suddenly stop taking Prochlorperazine without the consent of yourdoctor. It is important to continue taking this even if you feel well. Let yourdoctor know if your condition gets worse or does not improve.

Whatare the side effects of Prochlorperazine?

Common side effects:

  • Drowsiness
  • Dizziness
  • Sleep problems
  • Anxiety
  • Dry mouth
  • Strange dreams
  • Blurred vision
  • Stuffy nose
  • Breast swelling or discharge
  • Constipation
  • Weight gain
  • Missed menstrual periods
  • Impotence
  • Swelling in hands or feet
  • Mild itching
  • Trouble having an orgasm
  • Skin rash
  • Low blood pressure
  • Headache

Stop taking Prochlorperazine andcall your doctor right away if these occur:

  • Any new or unusual muscle movements you cannotcontrol
  • Tremors or shaking in your arms or legs
  • Uncontrolled muscle movements  in your face ( lip-smacking, chewing, tonguemovement, blinking or eye movement)
  • Little or no urinating
  • Stiffness or muscle spasms in your neck
  • Trouble swallowing
  • Fast or slow heart rate
  • A light-headed feeling
  • Low white blood cell counts
  • Severe nervous system reaction

Warningsand Precautions

  • This product is not recommended for use inchildren younger than 2 years or in children going through surgery.
  • This is also not recommended for use in elderlypeople with dementia.
  • Before taking a dose of Prochlorperazine, tellyour doctor if you have any medical history especially of breathing problems, liverdisease, stomach problems, or certain brain disorders.
  • Prochlorperazine may make you dizzy. Do not useany machinery or do anything that needs your alertness.
  • This medication may make you more sensitive to thesun. Limit your time in the sun. Use sunscreen and wear protective clothingwhen outdoors. Tell right away to your doctor if you get sunburned or have skinblisters.
  • This may also may you sweat less which makes youmore likely to get heatstroke. Avoid doing things that may cause you tooverheat.
  • During pregnancy, this drug should only be usedwhen needed. If you are breastfeeding women, consult your doctor first beforetaking a dose.
  • Let your doctor know if you have ever had anallergic reaction to this drug. Tell as well if you have any allergies. Thisproduct may have an inactive ingredient that causes an allergic reaction.