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Zidovudine

Zidovudine is used in pregnantwomen to prevent passing the...

Nimodipine

Nimodipine

General Information

Nimodipine is called a calcium-channel blocker used to lessen problems due to subarachnoid hemorrhage (SAH). SAH is a type of stroke that is life-threatening caused by bleeding into the space surrounding the brain. This condition can be caused by a ruptured aneurysm, head injury, or AVM. Nimodipine is a type of medicine that acts on the blood vessels. It narrows the blood vessels to slow blood flow to the area of bleeding.

How does Nimodipine work?

Nimodipine works by slowing the movement of calcium through the muscle cells. These are found in the walls of blood vessels. It does this by blocking calcium channels in these muscle cells. Calcium is needed by muscle cells for them to contract. By depriving them of calcium, this drug causes the muscle cells to relax. Nimodipine acts specifically on the muscle cells in the walls of arteries in the brain causing them to relax.

Why use Nimodipine?

Nimodipine relaxes narrowed blood vessels in the brain. This allows blood to flow more easily and stops the brain from being deprived of blood and thus oxygen. Nimodipine also reduces the risk of brain damage after a bleed on the surface of the brain. In 1988, this was approved for use to treat subarachnoid hemorrhage. This medication comes as a capsule for oral use. Each capsule is available as a 30 mg dosage strength.

How to use Nimodipine?

The recommended dosage is based on your condition, age, and response to the treatment. You must take this prescription exactly as it is given. Do not take more or less or often than instructed.

This drug is usually started assoon as possible after the start of bleeding in the brain, typically within 4days. This is taken every 4 hours or as directed by your doctor. The capsule isto be taken by mouth with a full glass of water. Take each dose at least anhour before or 2 hours after a meal. Remember to take it at the same time andin the same way each day.

What are the side effects of Nimodipine?

  • Dizziness
  • Headache
  • Flushing
  • Constipation
  • Nausea
  • Sweating
  • Fainting
  • Low blood pressure
  • Unusually fast or slow heartbeats

Warnings and Precautions

  • Tell your doctor if you have ever had heartdisease, high blood pressure, or cirrhosis.
  • Before using, let your doctor know if you areallergic to it. Tell as well if you have current medications.
  • Do not freeze this drug.
  • Keep at room temperature away from moisture orheat.