Latest Post

Formula Drugs

Pemetrexed

Pemetrexed is a prescription usedfor the treatment of lung...

Docefrez (Docetaxel)

Formula Drugs

Docetaxel General Information

Docefrez (Docetaxel) is indicated for:

  • Breast cancer

This is used in patients with locally advanced or metastatic breast cancer. It is after a failure or prior to chemotherapy.

  • Non-small cell lung cancer

Docefrez as a single agent is used in patients with locally advanced or metastatic non-small cell lung cancer. This is used in combination with cisplatin.

  • Prostate cancer

This is used in combination with prednisone. This is for the treatment of patients with androgen-independent (hormone-refractory) metastatic prostate cancer. 

How does Docefrez (Docetaxel) work?

Docefrez (Docetaxel) works by attacking the cancer cells. Every cell in the body has a supporting structure which is called the microtubular network. It is almost like a skeleton. If this ‘skeleton’ is changed or damaged, the cell can’t grow or reproduce. This drug makes the ‘skeleton’ in cancer cells unnaturally stiff so that these cells can no longer grow. 

Why use Docefrez (Docetaxel)?

Docefrez (Docetaxel) is an antineoplastic agent belonging to the taxoid family. It is white to an almost white powder. This is available for intravenous use. The Food and Drug Administration (FDA) has approved this medication. 

How to use Docefrez (Docetaxel)?

This is given intravenously by a healthcare professional. The range of the dosage is from 60mg/m2 to 100mg/m2 every 3 weeks. It is used along with other chemotherapy agents.

Your doctor may prescribe pre-medications like corticosteroids (dexamethasone) to prevent the side effects. These are generally started a day before the treatment and continued for a total of 3 days. Carefully follow your doctor’s instructions to prepare for your treatment. If you forget to take your pre-medication or you do not take it on schedule, let your doctor know before starting taking this medication.

What are the side-effects of Docefrez (Docetaxel)?

  • Vomiting, nausea, diarrhea
  • Loss of appetite
  • Constipation, muscle or joint pain
  • Feeling weak or tired
  • Mouth sores
  • Hair loss
  • Watery eyes or eye redness
  • Feeling short of breath
  • Altered sense of taste

Call your doctor right away if these happen:

  • Sudden vision problems
  • Redness or peeling of the skin on your arms or legs
  • Burning, numbness, or tingling in your hands or feet
  • Muscle weakness in your arms or legs
  • A feeling of being drunk (stumbling, confusion, or extreme drowsiness)

Warnings and Precautions

  • This may not be recommended for pregnant or breastfeeding women. Consult your doctor first before having this treatment.
  • Let your doctor if you are allergic to it or if you have any allergies.
  • Wash your hands well to prevent the spread of infections.