Abiraterone Acetate Tablets

August 01, 2020

Medicine

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AbirateroneAcetate is used for the treatment of prostate cancer that has already spread toother parts of the body. This is a type of medicine known as an androgenbiosynthesis inhibitor or an androgen. 

Prostatecancers are sensitive to testosterone and their growth is increased in thepresence of this hormone. Testosterone is produced by the testicles, theadrenal glands, and by cells in the prostate tumor itself. 

AbirateroneAcetate works by preventing the action of an enzyme called cytochrome P17. Theenzyme is also involved in the production of testosterone. This enzyme is foundin the testicles, the adrenal glands, and the tissues of the prostate tumor. Byinhibiting the activity of this enzyme in all these places, the amount oftestosterone in the body is reduced more than by medical castration. This helpsdecrease the growth of prostate cancer cells. 

Standardtreatment for prostate cancer that has spread beyond the prostate glandinvolves stopping the production of testosterone by the testicles. It is toslow the growth of the cancer cells. This is usually achieved with medicinescalled LHRH or gonadorelin analogs or with surgery to the testicles. 

Doctorsknow that prostate cancer begins when some cells in your prostate becomeabnormal. Mutations in the abnormal cells’ DNA cause the cells to grow morerapidly than normal cells do. The abnormal cells continue living when othercells would die. The accumulating abnormal cells form a tumor that can grow toinvade nearby tissue. Some abnormal cells can also break off and spread toother parts of the body.

Prostatecancer is one of the most common types of cancer in men. Cancer usuallygrows slowly and initially confined to the prostate gland. However, while sometypes of prostate cancer grow slowly and may need minimal or even no treatment.The prostate is a small walnut-shaped gland in men that creates the seminalfluid. More advanced prostate cancer may cause signs and symptoms such as:

• Trouble urinating
• Blood in semen
• Decreased force in the stream of urine
• Discomfort in the pelvic area
• Erectile dysfunction
• Bone pain

Factorsthat can increase your risk of prostate cancer include:

• Age – your risk of having this condition increases as you age
• Obesity – obese men diagnosed with prostate cancer may be more likely to have advanced disease that is more difficult to treat 
• Race – in black men, prostate cancer is more likely to be aggressive or advanced 
• Family history – if men in your family have had prostate cancer, your risk may be increased

Some tipson how to reduce your risk of prostate cancer;

1. Choosehealthy foods over supplements 

Nostudies have shown that supplements play a role in reducing your risk ofprostate cancer. Instead, choose foods that are rich in vitamins and mineralsso that you can maintain healthy levels of vitamins in your body.

• Maintain a healthy weight 

Work to maintainyour healthy weight by exercising most days of the week. If you need to loseweight, add more exercise, and reduce the number of calories you eat eachday. 

• Talk to your doctor about the increased risk ofprostate cancer 

Men witha high risk of prostate cancer may consider medications or other treatments toreduce their risk.

• Choose a healthy diet full of fruits and vegetables

Avoidhigh-fat foods and instead focus on choosing a variety of fruits, vegetables,and whole grains. Fruits and vegetables contain many vitamins and nutrientsthat can contribute to your health. Whether you can prevent prostate cancerthrough diet has yet to be conclusively proved. But eating a healthy diet witha variety of fruits and vegetables can improve your overall health.

How touse Abiraterone Acetate Tablets?

AbirateroneAcetate is to be taken by mouth on an empty stomach at least 1 hour before or 2hours after food. This is usually taken once a day or as directed by yourdoctor. The dosage is based on your mei9dcal condition and response to thetreatment. Taking this medicine with food greatly increases the amount of thedrug in your body and increases the risk of side effects as well. 

You needto swallow the whole medicine and don’t chew or break it. Use this medicationregularly to get the most benefit from it. To help you remember, take it at thesame time each day. Do not stop any prescription that has given for thetreatment of prostate cancer unless your doctor tells you to do so. Stoppingthe medications will allow cancer to spread more quickly. 

What arethe side effects of Abiraterone Acetate?

• Joint swelling or discomfort
• Diarrhea
• Fatigue
• Vomiting
• Shortness of breath
• Cough
• Edema
• Bruising
• High blood pressure
• Urinary tract infection 

If theseside effects persist or get worse, call your doctor right away. 

Precautions

• This drug may cause liver problems. For this reason, your doctor will want you to have blood tests to monitor your liver function. 
• Your blood pressure and the level of potassium in your blood should also be checked every month. You should tell your doctor if you have any signs of fluid retention. 
• Women who are or could be pregnant should wear gloves if they need to touch or handle Abiraterone Acetate. 
• Use this with caution in people with decreased liver function, severely decreased kidney function, or high blood pressure. People with a history of heart disease, with a low level of potassium in their blood, and on a low sodium diet, this medication should also be used with caution. 
• This is not for use in women and men with severely decreased liver function. 
• Abiraterone Acetate should not be taken by people with rare hereditary problems of galactose intolerance or glucose-galactose malabsorption. 
• This medicine should not be used if you are allergic to any of its ingredients. Please inform your doctor if you have previously experienced such an allergy. If you feel you have experienced an allergic reaction, stop using this medicine and inform your doctor right away.